Endocrine Abstracts

Aim: This study aims to evaluate patients with a diagnosis of pheochromocytoma.Method: This retrospective case–control study includes data from a tertiary endocrine center from January 1, 2010, to December 31, 2020. Demographic, laboratory, operation/pathology data of patients with pheochromocytoma were recorded.Results: A total of 38 patients (20 patients (52.6%) were male) were included in the study. Median age 48 years (17&...

Introduction: Although the replacement route is oral in most hypothyroid patients, euthyroidism cannot be achieved with oral therapy in some patients rarely (1). Although oral levothyroxine is used above the standard dose (1.6-1.9 mg/kg/day), there is resistance to oral therapy if there are laboratory and clinical signs of hypothyroidism (2). Crushing the drug and using it with vitamin C increases the absorption of levothyroxine (3). Rarely, some patients require lifelong intr...

Background: Subacute thyroiditis (SAT) is a transient thyrotoxic state characterized by suppressed TSH and low uptake of iodine 123 on thyroid scanning. SAT is a self limiting, possibly viral and inflammatory thyroid disorder that is usually associated with thyroid pain and systemic symptoms. Many factors can cause SAT. Infections are considered the most common cause. Vaccines can also lead to SAT.Case report: A 46-year-old male with a history of type 1 ...

Objective: Hereditary pituitary adenomas (PAs) are rare and occur either isolated or as part of a syndrome. Familial isolated pituitary adenoma (FIPA) is the presence of only PA in at least two members of a family, where “Aryl hydrocarbon receptor interacting protein-AIP” gene mutations have been identified in 10-20% of cases. However, the cause of tumorigenesis in the majority is unknown. We aimed to identify novel genetic variants in a cohort of FIPA patie...

Hypoparathyroidism is a rare endocrine disorder whose epidemiologic characteristics regarding the cause, clinical course, acute and chronic complications have not been well defined. There is also a substantial geographic variability regarding those parameters, and country-specific local data is scarce.This study was conducted to assess the baseline characteristics, including the demographics, etiologic distribution, disease severity, medications use...

Objective: Data on gender comparisons of diagnosis, management and prognostic factors in Cushing’s disease are very limited, however, there is no such a comparison in ectopic ACTH syndrome (EAS) in the literature. The aim of this study is to compare clinical and hormonal data, neuroendocrine tumor (NET) localization, treatment and survival outcomes in Cushing’s syndrome due to EAS by gender.Material-Methods: Eleven experienced centers from our ...

Purpose: To evaluate the relationship between basal dehydroepiandrosterone-sulfate (DHEA-S) levels and other tests used in the diagnosis and differential diagnosis of Cushing’s Syndrome (CS) among the patients with pathologically confirmed CS.Methods: In this multicenter study, the data of 623 patients with CS were evaluated retrospectively. The patients were classified as Group 1 (n = 353 Cushing’s disease;CD), Group 2 (n</e...

Aim: Thyroid Stimulating Hormone (TSH) suppression treatment may have a detrimental effect on bone tissue in differentiated thyroid cancer (DTC) patients. The current study aimed to investigate vertebral fracture, bone mineral density measurements, and TSH levels in DTC patients under levothyroxine (LT4) suppression treatment after total thyroidectomy and/or radioiodine ablation therapy in a multicentric setting.Material and Method: This multicentric cro...

Background: Treatment of vitamin D deficiency orinappropriate vitamin D supplementation may cause side effects associated with hypercalcemia. We observed a tendency to use very high single dose cholecalciferol for treatment of vitamin D deficiency.Aim: The primary aim of this study was to examine the clinical characteristics of patientswith very high serum 25OHD levels of vitamin D toxicity in Turkey.Materials and methods: An invit...

Background: Hypophysitis is a rare group of disease characterized with infla mmation of the pituitary gland. Rarity of the disease obviates development of a treatment strategy. We aimed to present the nationwide data of the demographics, clinical and radiological characteristics, treatment modalities and responses of the patients diagnosed with hypophysitis in a retrospective manner.Methods: The endocrinology clinics all over the country were invited to ...